Publications

2023
M.V. Ivanchenko and D.P. Corey. 2023. “Finding a window for gene therapy for hereditary deafness.” PNAS.
M.V. Ivanchenko, Daniel M. Hathaway, Alex J. Klein, Bifeng Pan, Olga Strelkova, Pedro De-la-Torre, Xudong Wu, Cole W. Peters, Eric M. Mulhall, Kevin T. Booth, Corey Goldstein, Joseph Brower, Marcos Sotomayor, Artur A. Indzhykulian, and D.P. Corey. 2023. “Mini-PCDH15 gene therapy rescues hearing in a mouse model of Usher syndrome type 1F.” Nature Communications.
2021
M.V. Ivanchenko, K.S. Hanlon, D.M. Hathaway, A.J. Klein, C.W. Peters, Y. Li, P.I. Tamvakologos, J. Nammour, C.M. Maguire, and D.P. Corey. 2021. “AAV-S: A versatile capsid variant for transduction of mouse and primate inner ear.” Molecular Therapy - Methods & Clinical Development.
M.V. Ivanchenko, A.I. Indzhykulian, and D.P. Corey. 2021. “Electron microscopy techniques for investigating structure and composition of hair-cell stereociliary bundles .” Frontiers in Cell and Developmental Biology.
K.T. Booth, Y. Hirsch, A.V. Vardaro, J. Ekstein, D. Yefet, A. Quint, T. Weiden, and D.P. Corey. 2021. “Identification of novel and recurrent variants in MYO15A in Ashkenazi Jewish patients with autosomal recessive nonsyndromic hearing loss and .” Frontiers in Genetics.
N. Akyuz, K.D. Karavitaki1, B. Pan, P.I. Tamvakologos, K.P. Brock, Y. Li, D.S. Marks, and D.P. Corey. 2021. “Mechanical gating of the auditory transduction channel TMC1 involves the fourth and sixth transmembrane helices .” bioRxiv.
E.M. Mulhall, A. Ward, D. Yang, M.A. Koussa, D.P. Corey, and W.P. Wong. 2021. “Single-molecule force spectroscopy reveals the dynamic strength of the hair-cell tip-link connection .” Nature Comms.
2020
M.V. Ivanchenko, K.S. Hanlon, M.K. Devine, K. Tenneson, F. Emond, J.F. Lafond, M.A. Kenna, D.P. Corey, and C.A. Maguire. 2020. “ Preclinical testing of AAV9-PHP.B for transgene expression in the non-human primate cochlea.” Hearing Research.
M.V. Ivanchenko, M. Cicconet, H. Al Jandal, X. Wu, D.P. Corey, and A.A. Indzhykulian. 2020. “Serial scanning electron microscopy of anti-PKHD1L1 immuno-gold labeled mouse hair cell stereocilia bundles .” Scientific Data.
D.P. Corey and C.A. Maguire. 2020. “Viral vectors for gene delivery to the inner ear .” Hearing Research.
2019
B. György, C. Nist-Lund, B. Pan, Y. Asai, K.D. Karavitaki, B. Kleinstiver, S.P. Garcia, M.P. Zaborowski, P. Solanes, S. Spataro, B. Schneider, J.K. Joung, G.S.G. Geleoc, J.R. Holt, and D.P. Corey. 2019. “Allele-specific gene editing prevents deafness in a model of dominant progressive hearing loss .” Nature Medicine .
K.S Hanlon, Kleinstiver, B.P., S. ., Garcia, Zaborowski, M., A. Volak, S.E. Spirig, A. Muller, A.A. Sousa, S. Tsai, N.E. Bengtsson, C. Loov, M. Ingelsson, J.S. Chamberlain, D.P. Corey, M. Aryee, J.K. Joung, X.O. Breakefield, C.A. Maguire, and B. György. 2019. “High levels of AAV vector integration into CRISPR-induced DNA breaks .” Nature Comms.
X. Wu, M.V. Ivanchenko, H. Al Jandal, M. Cicconet, A.A. Indzhykulian, and D.P. Corey. 2019. “PKHD1L1 is a coat protein of hair-cell stereocilia and is required for normal hearing .” Nature Comm.
2018
B. György, E.J. Meijer, M.V. Ivanchenko, K. Tenneson, F. Emond, K.S. Hanlon, A.A. Indzhykulian, A. Volak, K.D. Karavitaki, P. Tamvakologos, M. Vezina, V.K. Berezovskii, R.T. Born, M. O’Brien, J-F. Lafond, Y. Arsenijevic, M.A. Kenna, C.A. Maguire, and D.P. Corey. 2018. “Gene transfer with AAV9-PHP.B rescues hearing in a mouse model of Usher syndrome 3A and transduces hair cells in a non-human primate .” Molecular Therapy: Methods & Clinical Development .
J.F. Krey, D.I. Scheffer, D. Choi, A. Reddy, L.L. David, D.P. Corey, and P.G. Barr-Gillespie. 2018. “Mass spectrometry quantitation of proteins from small pools of developing auditory and vestibular cells .” Sci. Data.
B. Pan, N. Akyuz, X-P. Liu, Y. Asai, C. Nist-Lund, K. Kurima, B.H. Derfler, B. György, W. Limapichat, Walujkar, S., L.N. Wimalasena, M. Sotomayor, D.P. Corey, and J.R. Holt. 2018. “TMC1 forms the pore of mechanosensory transduction channels in mammalian inner ear hair cells .” Neuron.
D.P. Corey, N. Akyuz, and J.R. Holt. 2018. “Function and dysfunction of TMC channels in inner ear hair cells.” Cold Spring Harb. Perspect. Med.
2017
M.R. Avenarius, J.F. Krey, R.A. Dumont, C.P. Morgan, C. Benson, S. Vijayakumar, C. Cunningham, D. Scheffer, D.P. Corey, Müller, U., S.M. Jones, and P.G. Barr-Gillespie. 2017. “Heterodimeric capping protein is required for stereocilia length and width regulation. .” J. Cell Biol.
Gyorgy, B., Sage, C., A.A. Indzhykulian, Scheffer, D.I., A.R. Brisson, S. Tan, X. Wu, A. Volak, Mu, D., P Tamvakologos, Y. Li, Z. Fitzpatrick, Ericsson, M., X.O. Breakfield, D.P. Corey, and C.A. Maguire. 2017. “Rescue of hearing by gene delivery to inner-ear hair cells using exosome-associated AAV. .” Molecular Therapy.
2016
D.P. Corey and J.R. Holt. 2016. “Are TMCs the mechanotransduction channels of vertebrate hair cells? .” J. Neurosci.

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